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U.S. Patent and Trademark Office issues 9th and 10th CRISPR patents to CVC July 23, 2019

On July 23, 2019 the U.S. Patent and Trademark Office issued U.S. Patent Nos. 10,358,658 and 10,358,659 (‘the ‘658 and ‘659 patents respectively) to The Regents of the University of California, the University of Vienna, and Dr. Emmanuelle Charpentier (collectively, “CVC”). The ‘658 patent covers CRISPR methods for targeting and binding, modifying or cleaving a target DNA using single guide RNAs, and the ‘659 patent covers CRISPR methods for targeting and binding, modifying or cleaving a target DNA with a Cas9 protein that contains a mutation in a RuvC and/or HNH domain and a single guide RNA. Both the ‘658 and ‘659 patents claim earliest priority to a U.S. provisional application, filed by CVC on May 25, 2012.

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